An Analyst/Technician position is immediately available in the TIGET Clinical Lab (TCL) coordinated by dr. Matias Soncini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, Italy.

The Institute

SR-Tiget was created in 1995 as a joint-venture between Fondazione Telethon and Ospedale San Raffaele (OSR), with the mission to perform cutting edge research on gene and cell therapy and to translate its results into therapeutic advances for genetic diseases. The Institute is located within the OSR campus, which includes a large multi-disciplinary research hospital, a biomedical research center, a university and also hosts several biotechnologies companies. Over the years, SR-Tiget has given a pioneering contribution to the gene and cell therapy field with relevant discoveries in vector design, gene transfer and gene editing strategies, stem cell biology, identity and mechanism of action of regulatory cells in immune responses and innate immune cells in cancer. SR-Tiget has also established the resources and framework for translating these advances into novel experimental therapies and has implemented several successful gene therapy clinical trials, which have already treated >120 patients and led to the filing and approval of novel advanced therapy medicines.

The position

We are looking for a motivated Analyst/Technician to work in TCL, part of the Development Units of TIGET. TCL is a Clinical Research laboratory that performs analysis on samples from patients that underwent experimental Gene Therapy. TCL is an AIFA autocertified Phase I laboratory where the biological effects of experimental Gene Therapy are studied following approved Clinical Protocols and in compliance with Good Clinical Laboratory Practice (GCLP).

Main tasks

  • Direct involvement in wet lab activities
  • Managing and tracking of biological samples following GCLP principles
  • Compiling all the Quality documentation related to the laboratory activity
  • Collaboration in the preparation of Standard Operative Procedures

Basic Qualifications and Skills:

  • Scientific Bachelor or Master’s Degree with strong wet lab experience
  • Experience in ex-vivo cellular biology
  • Experience in cytofluorimetric analysis is a plus
  • Knowledge of primary cell purification from blood and bone marrow
  • High accuracy, reliability, precision
  • Ability to work autonomously
  • Ability to follow Standardized Procedures, prioritize and manage multiple tasks
  • Friendly, collaborative, pro-active mindset
  • Good oral and written English

Additional Qualifications and Skills for a Senior candidate:

  • Pluriannual experience of the above-described skills
  • Experience in preparing scientific documentations (Grants, papers, reports)
  • Basic knowledge of Molecular Biology techniques
  • Experience in GXP laboratories: ALCOA data recording, SOP, Non-Conformity, CAPA management

We offer

  • Competitive salary depending on qualifications and experience.
  • A dynamic environment and the chance to give important contribution to clinical translation of innovative ATMP

Applications, including a CV, should be sent by e-mail to soncini.matias@hsr.it. Evaluation of applications/interviews will begin immediately and continue until the position is filled.

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