ROLE OF BDNF AND TRKB IN EPILEPTOGENESIS: IMPLICATIONS FOR PHARMACOLOGICAL AND GENETIC TREATMENT

Pubblicazioni Scientifiche

• EPILEPSIA

  Different patterns of induction of fibroblast growth factor-2 and brain-derived neurotrophic factor messenger RNAs during kindling epileptogenesis, and development of a herpes simplex vector for fibroblast growth factor-2 gene transfer in vivo

• EPILEPSIA

  Dendritic targeting of mRNAs for plasticity genes in experimental models of temporal lobe epilepsy

• EUROPEAN JOURNAL OF NEUROSCIENCE

  TRKB signalling controls the expression of N-methyl-D-aspartate receptors in the visual cortex

• GENE THERAPY

  Effects of defective herpes simplex vectors expressing neurotrophic factors on the proliferation and differentiation of nervous cells in vivo

• JOURNAL OF NEUROSCIENCE

  Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway

• JOURNAL OF NEUROSCIENCE

  Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis

• NEUROREPORT

  Differential somato-dendritic localization of TrkA, TrkB, TrkC and p75 mRNAs in vivo