MOLECULAR AND CELLULAR BIOLOGY OF LENTIVIRAL VECTOR-MEDIATED GENE TRANSFER AND EXPRESSION

Pubblicazioni Scientifiche

• BIOCHEMICAL JOURNAL

  Treatment of the mouse model of mucopolysaccharidosis type IIIB with lentiviral-NAGLU vector

• BLOOD

  Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence

• BLOOD

  Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice

• CANCER CELL

  Targeting the tumor and its microenvironment by a dual-function decoy Met receptor

• CANCER GENE THERAPY

  RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis

• CELL

  Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity

• HUMAN GENE THERAPY

  In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors

• HUMAN GENE THERAPY

  Gene therapy for a mucopolysaccharidosis type I murine model with lentiviral-IDUA vector

• HUMAN GENE THERAPY

  Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses

• HUMAN GENE THERAPY

  Gene therapy of storage disorders by retroviral and lentiviral vectors

• JOURNAL OF CLINICAL INVESTIGATION

  An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice

• MOLECULAR THERAPY

  Efficient Tet-dependent expression of human factor IX in vivo by a new self-regulating lentiviral vector

• MOLECULAR THERAPY

  Axons mediate the distribution of arylsulfatase A within the mouse hippocampus upon gene delivery

• NATURE BIOTECHNOLOGY

  Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters

• NUCLEIC ACIDS RESEARCH

  Deletion in a (T)8 microsatellite abrogates expression regulation by 3′-UTR

• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

  Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors

• VIROLOGY

  Molecular evidence of inefficient transduction of proliferating human B lymphocytes by VSV-pseudotyped HIV-1-derived lentivectors