GDNF/GRFA1/RET MULTICOMPONENT RECEPTOR DYSFUNCTIONS IN HIRSCHSPRUNG`S DISEASE
- 2 Anni 1999/2001
- 103.291€ Totale Fondi
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Pubblicazioni Scientifiche
- AMERICAN JOURNAL OF PATHOLOGY
The RetC620R mutation affects renal and enteric development in a mouse model of Hirschsprung's disease
- CANCER RESEARCH
PP1 inhibitor induces degradation of RETMEN2A and RETMEN2B oncoproteins through proteosomal targeting
- CANCER RESEARCH
RET is constitutively activated by novel tandem mutations that alter the active site resulting in multiple endocrine neoplasia type 2B
- CELLULAR SIGNALLING
RET oncoproteins induce tyrosine phosphorylation changes of proteins involved in RNA metabolism
- MOLECULAR ENDOCRINOLOGY
A novel activating mutation in the RET tyrosine kinase domain mediates neoplastic transformation