ALTERATIONS IN CA2+ HOMEOSTASIS IN ANIMAL MODELS OF MUSCULAR DYSTROPHY

Pubblicazioni Scientifiche

• 2007 CELL DEATH AND DIFFERENTIATION

  Mitochondrial Ca2+ as a key regulator of cell life and death

• 2004 NEUROBIOLOGY OF DISEASE

  The presenilin 2 M239I mutation associated with familial Alzheimer's disease reduces Ca2+ release from intracellular stores

• 2003 ONCOGENE

  Calcium and apoptosis: facts and hypotheses

• 2004 JOURNAL OF BIOLOGICAL CHEMISTRY

  Mitochondrial pH monitored by a new engineered green fluorescent protein mutant

• 2001 JOURNAL OF BIOLOGICAL CHEMISTRY

  Alteration in calcium handling at the subcellular level in mdx myotubes

• 2008 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME

  Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: Role of calcineurin/NFAT as Ca2+ signal integrators

• 2001 EMBO JOURNAL

  The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

• 2008 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

  Cardiac cell hypertrophy in vitro: Role of calcineurin/NFAT as Ca2+ signal integrators

• 2005 CELL CALCIUM

  Improved strategies for the delivery of GFP-based Ca2+ sensors into the mitochondrial matrix

• 2000 NATURE CELL BIOLOGY

  A genetically encoded, fluorescent indicator for cyclic AMP in living cells

• 2008 JOURNAL OF BIOLOGICAL CHEMISTRY

  Calcium dynamics in the peroxisomal lumen of living cells

• 2006 PHYSIOLOGICAL REVIEWS

  Microdomains of intracellular Ca2+: Molecular determinants and functional consequences

• 2003 JOURNAL OF BIOLOGICAL CHEMISTRY

  Stable interactions between mitochondria and endoplasmic reticulum allow rapid accumulation of calcium in a subpopulation of mitochondria

• 2005 NEUROBIOLOGY OF DISEASE

  Reduction of Ca2+ stores and capacitative Ca2+ entry is associated with the familial Alzheimer's disease presenilin-2 T122R mutation and anticipates the onset of dementia

• 2004 JOURNAL OF CELL BIOLOGY

  In vivo monitoring of Ca2+ uptake into mitochondria of mouse skeletal muscle during contraction

• 2006 JOURNAL OF CELL BIOLOGY

  Direct in vivo monitoring of sarcoplasmic reticulum Ca2+ and cytosolic cAMP dynamics in mouse skeletal muscle

• 2001 EMBO JOURNAL

  Beat-to-beat oscillations of mitochondrial [Ca2+] in cardiac cells

• 2009 BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

  Measurements of mitochondrial calcium in vivo